Penalty method for source reconstruction of multispectral bioluminescence tomography
作者: Qiyue LiJingjing YuWenbin XiangXiaowei He
作者单位: 1Shaanxi Normal University
2Northwest University
刊名: Optical Engineering, 2018, Vol.57 (8), pp.083104-083104
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.OE.57.8.083104
关键词: TomographyImage reconstruction techniquesMedical and biological imagingInverse problems
原始语种摘要: Bioluminescence tomography (BLT) is a promising optical molecular imaging technique in preclinical research. One key problem for BLT is how to deal with the severe ill-posedness and obtain accurate and stable reconstruction. We propose a penalty method for recovering bioluminescence sources, in which we transform reconstruction of BLT into an L 1/2-norm penalty problem and solve it via a nonmonotone proximal gradient method with a suitable penalty parameter update scheme. Simulations and phantom experiments based on multispectral measurements were designed to evaluate the proposed reconstruction method. The encouraging results show that the proposed method has better reconstruction accuracy and image quality than the comparative methods.
全文获取路径: SPIE  (合作)

  • reconstruction 复原
  • multispectral 多重谱的
  • tomography 断层x 线摄影
  • recovering 恢复
  • propose 提议
  • phantom 受精台
  • imaging 图像形成
  • penalty 罚款
  • method 方法
  • accurate 精确的