In vivo photoacoustic tomography of myoglobin oxygen saturation
作者: Li LinJunjie YaoLei LiLihong V. Wang
作者单位: 1Washington University in St. Louis
刊名: Journal of Biomedical Optics, 2016, Vol.21 (6), pp.061002-061002
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.21.6.061002
关键词: myoglobinoxygen saturationcalibration-free photoacoustic tomographybackbone muscle
原始语种摘要: Myoglobin is an essential oxygen-binding hemoprotein in skeletal and cardiac muscles that buffers intracellular oxygen ( O 2 ) concentration in response to hypoxia or elevated muscle activities. We present a method that uses photoacoustic computed tomography to measure the distribution of myoglobin in tissue and the oxygen saturation of myoglobin ( sO 2 - Mb ). From photoacoustic measurements of mice in different oxygenation states, we performed calibration-free quantification of the sO 2 - Mb change in the backbone muscle in vivo .
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • myoglobin 肌红蛋白
  • photoacoustic 光声的
  • oxygen 
  • muscle 肌肉
  • saturation 饱和
  • hemoprotein 血红素蛋白
  • tomography 断层x 线摄影
  • hypoxia 氧过少
  • calibration 校准
  • cardiac 贲门