Line-field confocal optical coherence tomography for high-resolution noninvasive imaging of skin tumors
作者: Arnaud DuboisOlivier LevecqHicham AzimaniDavid SiretAnaïs BarutMariano SuppaVéronique del MarmolJosep MalvehyElisa CinottiPietro RubegniJean-Luc Perrot
作者单位: 1Université Paris-Saclay
2DAMAE Medical
3Hôpital Erasme
4University Hospital Clinic of Barcelona
5University of Siena
6University Hospital of Saint-Etienne
刊名: Journal of Biomedical Optics, 2018, Vol.23 (10), pp.106007-106007
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.23.10.106007
关键词: Optical coherence tomographySkin cancerOptical imagingConfocal microscopy
原始语种摘要: An optical technique called line-field confocal optical coherence tomography (LC-OCT) is introduced for high-resolution, noninvasive imaging of human skin in vivo . LC-OCT combines the principles of time-domain optical coherence tomography and confocal microscopy with line illumination and detection using a broadband laser and a line-scan camera. LC-OCT measures the echo-time delay and amplitude of light backscattered from cutaneous microstructures through low-coherence interferometry associated with confocal spatial filtering. Multiple A-scans are acquired simultaneously while dynamically adjusting the focus. The resulting cross-sectional B-scan image is produced in real time at 10 frame / s. With an isotropic spatial resolution of ∼1 μm, the LC-OCT images reveal a comprehensive...
全文获取路径: SPIE  (合作)
影响因子:2.881 (2012)

  • coherence 相干性
  • imaging 图像形成
  • tomography 断层x 线摄影
  • optical 光学的
  • confocal 共焦
  • illumination 光照强度
  • camera 摄影机
  • microscopy 显微镜检查
  • spatial 空间的
  • resolution 分解能力