Modified forward model for eliminating the time-varying impact in fluorescence molecular tomography
作者: Wei HeGuanglei ZhangHuangsheng PuFei LiuXu CaoJianwen LuoJing Bai
作者单位: 1Tsinghua University
2Xidian University
刊名: Journal of Biomedical Optics, 2014, Vol.19 (5), pp.056012-056012
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.19.5.056012
关键词: fluorescence molecular tomographyforward modelimage reconstructiontime-varying
原始语种摘要: In conventional fluorescence molecular tomography, the distribution of fluorescent contrast agents is reconstructed with the assumption of constant concentration during data acquisition for each image frame. However, the concentration of fluorescent contrast target is usually time-varying in experiments or in-vivo studies. In this case, the reconstruction methods cannot be directly applied to the fluorescence measurements without considering the time-varying effects of concentration. We propose a modified forward model by dividing the fluorescence yield distribution into two parts: one is a constant representing the spatial distribution of the fluorescent target and the other is an impact factor representing the effects of the concentration change and other possible factors. By extracting...
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • varying 变化的
  • tomography 断层x 线摄影
  • forward 促进
  • reconstruction 复原
  • representing 表示
  • fluorescence 荧光
  • reconstructed 修]重构[建
  • model 模型
  • phantom 受精台
  • concentration 浓度