Reconstruction of high-resolution early-photon tomography based on the first derivative of temporal point spread function
作者: Jiaju ChengChuangjian CaiJianwen Luo
作者单位: 1Tsinghua University
刊名: Journal of Biomedical Optics, 2018, Vol.23 (6), pp.060503-060503
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.23.6.060503
关键词: Fluorescence molecular tomographyEarly photonDerivativeHigh resolutionImage reconstruction
原始语种摘要: For fluorescence molecular tomography, higher spatial resolution can be achieved using minimally scattered early photons. Conventional reconstruction methods of early photon tomography (EPT) are based on the integral of temporal point spread function (TPSF), which may lead to poor image quality due to systematic noise and time mismatch between the TPSF data and forward model. The derivative of the rising portion of TPSF is proposed to be used in EPT to increase the performance of reconstruction because the derivative is less sensitive to noise and time mismatch than the integral. A method based on projected Tikhonov regularization with the reconstructed result of steepest descent algorithm as a priori information is developed. Using the derivative of TPSF, the method can achieve high...
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • tomography 断层x 线摄影
  • temporal 现世的
  • spread 散布
  • reconstruction 复原
  • point 
  • derivative 衍生物
  • photon 光量子
  • regularization 正则化
  • reconstructed 修]重构[建
  • achieve 达到