Handheld optical-resolution photoacoustic microscopy
作者: Li LinPengfei ZhangSong XuJunhui ShiLei LiJunjie YaoLidai WangJun ZouLihong V. Wang
作者单位: 1Washington University in St. Louis
2Texas A&M University
刊名: Journal of Biomedical Optics, 2017, Vol.22 (4), pp.041002-041002
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.22.4.041002
关键词: photoacoustic handheld probeoptical-resolution photoacoustic microscopytwo-axis microelectromechanical system mirrorconfocal scanninghuman skin imaging
原始语种摘要: Optical-resolution photoacoustic microscopy (OR-PAM) offers label-free in vivo imaging with high spatial resolution by acoustically detecting optical absorption contrasts via the photoacoustic effect. We developed a compact handheld OR-PAM probe for fast photoacoustic imaging. Different from benchtop microscopes, the handheld probe provides flexibility in imaging various anatomical sites. Resembling a cup in size, the probe uses a two-axis water-immersible microelectromechanical system mirror to scan both the illuminating optical beam and resultant acoustic beam. The system performance was tested in vivo by imaging the capillary bed in a mouse ear and both the capillary bed and a mole on a human volunteer.
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • optical 光学的
  • photoacoustic 光声的
  • microscopy 显微镜检查
  • probe 探针
  • imaging 图像形成
  • illuminating 照明用的灯饰用的
  • immersible 可浸
  • detecting 检测
  • spatial 空间的
  • human 人的