Enhanced spatial resolution in fluorescence molecular tomography using restarted L1-regularized nonlinear conjugate gradient algorithm
作者: Junwei ShiFei LiuGuanglei ZhangJianwen LuoJing Bai
作者单位: 1Tsinghua University
2Tsinghua-Peking Center for Life Sciences
刊名: Journal of Biomedical Optics, 2014, Vol.19 (4), pp.046018-046018
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.19.4.046018
关键词: fluorescence molecular tomographyenhanced spatial resolutionL1 regularizationrestarted strategy
原始语种摘要: Owing to the high degree of scattering of light through tissues, the ill-posedness of fluorescence molecular tomography (FMT) inverse problem causes relatively low spatial resolution in the reconstruction results. Unlike L2 regularization, L1 regularization can preserve the details and reduce the noise effectively. Reconstruction is obtained through a restarted L1 regularization-based nonlinear conjugate gradient (re-L1-NCG) algorithm, which has been proven to be able to increase the computational speed with low memory consumption. The algorithm consists of inner and outer iterations. In the inner iteration, L1-NCG is used to obtain the L1-regularized results. In the outer iteration, the restarted strategy is used to increase the convergence speed of L1-NCG. To demonstrate the performance...
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • regularization 正则化
  • algorithm 算法
  • gradient 倾斜度
  • spatial 空间的
  • tomography 断层x 线摄影
  • nonlinear 非线性的
  • reconstruction 复原
  • phantom 受精台
  • computational 计算的
  • iteration 迭代