Deep-tissue temperature mapping by multi-illumination photoacoustic tomography aided by a diffusion optical model: a numerical study
作者: Yuan ZhouEric TangJianwen LuoJunjie Yao
作者单位: 1Tsinghua University
2Duke University
刊名: Journal of Biomedical Optics, 2018, Vol.23 (1), pp.016014-016014
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.23.1.016014
关键词: Photoacoustic tomographyTemperature mappingMulti-illuminationOptical diffusion modelThermotherapy
原始语种摘要: Temperature mapping during thermotherapy can help precisely control the heating process, both temporally and spatially, to efficiently kill the tumor cells and prevent the healthy tissues from heating damage. Photoacoustic tomography (PAT) has been used for noninvasive temperature mapping with high sensitivity, based on the linear correlation between the tissue’s Grüneisen parameter and temperature. However, limited by the tissue’s unknown optical properties and thus the optical fluence at depths beyond the optical diffusion limit, the reported PAT thermometry usually takes a ratiometric measurement at different temperatures and thus cannot provide absolute measurements. Moreover, ratiometric measurement over time at different temperatures has to assume that the tissue’s optical...
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • illumination 光照强度
  • optical 光学的
  • temperature 温度
  • tomography 断层x 线摄影
  • diffusion 扩散
  • reconstructed 修]重构[建
  • mapping 映象
  • model 模型
  • absolute 绝对的
  • aided 半自动