Development of a large scale production of 67 Cu from 68 Zn at the high energy proton accelerator: Closing the 68 Zn cycle
作者: Dmitri G. MedvedevLeonard F. MausnerGeorge E. MeinkenSlawko O. KurczakHenry SchnakenbergCleveland J. DodgeElizabeth M. KorachSuresh C. Srivastava
作者单位: 1Collider Accelerator Department, Brookhaven National Laboratory, Upton, NY 11793, USA
刊名: Applied Radiation and Isotopes, 2011, Vol.70 (3), pp.423-429
来源数据库: Elsevier Journal
DOI: 10.1016/j.apradiso.2011.10.007
关键词: Copper-67Zinc-68RadiotherapyHigh energy reactionBLIPChemical separation
原始语种摘要: Abstract(#br)A number of research irradiations of 68 Zn was carried out at Brookhaven Linac Isotope Producer aiming to develop a practical approach to produce the radioisotope 67 Cu through the high energy 68 Zn(p,2p) 67 Cu reaction. Disks of enriched zinc were prepared by electrodeposition of 68 Zn on aluminum or titanium substrate and isolated in the aluminum capsule for irradition. Irradiations were carried out with 128, 105 and 92MeV protons for at least 24h. After irradiation the disk was chemically processed to measure production yield and specific activity of 67 Cu and to reclaim the target material. The recovered 68 Zn was irradiated and processed again. The chemical procedure comprised BioRad cation exchange, Chelex-100 and anion exchange...
全文获取路径: Elsevier  (合作)
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影响因子:1.179 (2012)

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