Multimodality treatment of neuroendocrine liver metastases
作者: Koray KarabulutHizir Yakup AkyildizCraig LanceFederico AucejoGordon McLennanOrhan AgcaogluAllan SipersteinEren Berber
作者单位: 1Liver Tumor Ablation Program, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH
2Department of Radiology, Cleveland Clinic, Cleveland, OH
3Department of Hepato-Pancreato-Biliary and Transplant Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH
刊名: Surgery, 2011, Vol.150 (2), pp.316-325
来源数据库: Elsevier Journal
DOI: 10.1016/j.surg.2011.05.008
英文摘要: Background(#br)Neuroendocrine liver metastases have a distinct tumor biology and symptomatology that render their management challenging. This difficulty is reflected in the literature, which lacks consensus on a treatment algorithm. The aim of this study is to propose a treatment algorithm based on patient morbidity and the efficacy of different treatment options.(#br)Methods(#br)The medical records of 127 patients with neuroendocrine liver metastases were reviewed. As first-line treatment, 69 of these patients underwent radiofrequency ablation (RFA), 29 patients were treated by liver resection, and 29 underwent embolization. Clinical characteristics and surgical parameters were analyzed with the chi-square test, and cumulative survival was analyzed with the Kaplan-Meier method. All data...
全文获取路径: Elsevier  (合作)
影响因子:3.373 (2012)