Prolonged Psychosis Associated With Interferon Therapy in a Patient With Hepatitis C: Case Study and Literature Review
作者: Yi-Chun ChengChun-Chih ChenAi-Sheng HoNan-Ying Chiu
作者单位: 1The Dept. of Psychiatry, Chang-Hua Christian Hospital, Chang-Hua, Taiwan
2The Division of Gastroenterology, Dept. of Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan
刊名: Psychosomatics, 2009, Vol.50 (5), pp.538-542
来源数据库: Elsevier Journal
DOI: 10.1016/S0033-3182(09)70848-5
原始语种摘要: Background(#br)Although rare, psychosis can emerge during interferon (IFN)-alpha therapy and persist after therapy is completed.(#br)Objective(#br)The authors report the case of a 30-year-old man with hepatitis C infection treated with IFN-alpha and ribavirin who developed acute psychosis with persecutory delusions and auditory hallucinations, resulting in a suicide attempt.(#br)Method(#br)The patient was treated with amisulpride for 6 weeks and then with risperidone for 6 weeks.(#br)Results(#br)There was no improvement in symptoms until the patient was treated with quetiapine; he then had a marked recovery from the psychotic symptoms. The duration of the psychosis was 28 weeks.(#br)Conclusion(#br)Hepatitis C can be successfully treated with IFN therapy, and the risk of IFN-induced...
全文获取路径: Elsevier  (合作)
影响因子:1.732 (2012)