Unusual amnesia in a patient with VGKC-Ab limbic encephalitis: A case study
作者: Luke D. KartsounisRajith de Silva
作者单位: 1Essex Neurosciences Centre, Queen's Hospital, Romford, Essex, UK
刊名: Cortex, 2010, Vol.47 (4), pp.451-459
来源数据库: Elsevier Journal
DOI: 10.1016/j.cortex.2010.01.009
关键词: VGKC-AbImmuno-suppressionMemory variabilityConfabulations
英文摘要: Abstract(#br)We describe the case of a patient with confirmed voltage-gated potassium channel antibody-associated encephalitis (VGKC-Ab). MRI studies revealed bilateral hyper-intensity in the hippocampi, with their volumes preserved. At presentation, the patient's anterograde and retrograde memory skills were found to be impaired and he showed fluctuation in his ability to recall familiar information. Following treatment with immunotherapy, his condition improved considerably and, in a series of follow up assessments, he performed satisfactorily (i.e., within the average range or above) on formal tests of memory, as well as on a range of other cognitive tests, including tests of executive function. By contrast, in the context of contemporaneous unstructured interviews, he showed a strong...
全文获取路径: Elsevier  (合作)
影响因子:6.161 (2012)