Gender-dependent associations of CDKN2A / 2B , KCNJ11 , POLI , SLC30A8 , and TCF7L2 variants with type 2 diabetes in (North African) Tunisian Arabs
作者: Amira TurkiGhadeer S. Al-ZabenMoncef KhirallahHela MarmouchTouhami MahjoubWassim Y. Almawi
作者单位: 1Research Unit of Biology and Genetics of Hematological and Autoimmune diseases, Faculty of Pharmacy of Monastir, University of Monastir, Monastir, Tunisia
2Department of Medical Biochemistry, Arabian Gulf University, Manama, Bahrain
3Department of Ophthalmology, CHU Fattouma Bourguiba, Monastir, Tunisia
4Department of Endocrinology, CHU Fattouma Bourguiba, Monastir, Tunisia
刊名: Diabetes Research and Clinical Practice, 2014, Vol.103 (3), pp.e40-e43
来源数据库: Elsevier Journal
DOI: 10.1016/j.diabres.2013.12.040
关键词: Genetic association studiesSingle nucleotide polymorphismsType 2 diabetes
原始语种摘要: Abstract(#br)We investigated the impact of gender on T2DM association with confirmed susceptibility loci. CDKN2A / 2B rs10811661, KCNJ11 rs5219, and TCF7L2 rs7903146 were associated with T2DM in females, while POLI rs488846 was associated with T2DM among males; the association of SLC30A8 rs13266634 and TCF7L2 rs4506565, rs12243326, and rs12255372 with T2DM was gender-independent.
全文获取路径: Elsevier  (合作)
影响因子:2.741 (2012)

  • nucleotide 核苷酸
  • diabetes 糖尿病
  • TCF Trim Centering and Feel
  • association 联合
  • confirmed 已确认的
  • gender 性别
  • independent 独立的
  • associated 相关的
  • susceptibility 磁化率
  • among 在当中