Prokineticin 1 and leukemia inhibitory factor mRNA expression in the endometrium of women with idiopathic recurrent pregnancy loss
作者: Abdullah KaraerYilmaz CigremisEbru CelikRukiye Urhan Gonullu
作者单位: 1Department of Obstetrics and Gynecology, Inonu University, School of Medicine, Malatya, Turkey
2Department of Medical Biology and Genetics, Inonu University, School of Medicine, Malatya, Turkey
刊名: Fertility and Sterility, 2014, Vol.102 (4), pp.1091-1095.e1
来源数据库: Elsevier Journal
DOI: 10.1016/j.fertnstert.2014.07.010
关键词: Leukemia inhibitory factor (LIF)prokineticin 1 (PROK1)recurrent pregnancy loss
英文摘要: Objective(#br)To determine the expression patterns of prokineticin 1 (PROK1) and leukemia inhibitory factor (LIF) mRNA differ in peri-implantation endometrial tissue of women with idiopathic recurrent pregnancy loss (RPL) from normal fertile women.(#br)Design(#br)A case-control study.(#br)Setting(#br)University-based tertiary care center.(#br)Patient(s)(#br)30 women with idiopathic RPL and 30 fertile controls.(#br)Intervention(s)(#br)Endometrial biopsies.(#br)Main Outcome Measure(s)(#br)Real-time polymerase chain reaction analysis for expression of PROK1 and LIF mRNA.(#br)Result(s)(#br)The expression of PROK1 and LIF was statistically significantly increased in the endometrium of the women with idiopathic RPL compared with the controls. Furthermore, increased LIF expression was observed...
全文获取路径: Elsevier  (合作)
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影响因子:4.174 (2012)

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