Reductions in virological failure and drug resistance to antiretroviral therapy in Chinese patients associated with lamivudine-based regimens, 2003–12: a cross-sectional study
作者: Hui XingYuhua RuanJenny H HsiWei KanLingjie LiaoXuebing LengJing WangCui HeYiming Shao
作者单位: 1State Key Laboratory of Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China
刊名: The Lancet, 2015, Vol.386 , pp.S60-S60
来源数据库: Elsevier Journal
DOI: 10.1016/S0140-6736(15)00641-8
原始语种摘要: Abstract(#br)Background(#br)China's National Free Antiretroviral Treatment Program has substantially scaled up and standardised antiretroviral treatment (ART) since 2008. Meanwhile, no study worldwide has examined the effects of rapid ART programme scale-up on treatment outcomes in resource-limited settings on a large scale.(#br)Methods(#br)The national HIV drug resistance surveillance database included annual cross-sectional surveys HIV drug resistance from 2003–12. We used China's national HIV drug resistance surveillance database to determine virological failure, acquired drug resistance, and poor adherence after 12–15 months of first-line ART. The probability proportional to proxy size (PPPS) sampling recommended by WHO was used in this study. χ tests and logistic regression were used...
全文获取路径: Elsevier  (合作)
影响因子:39.06 (2012)