Reactions of 2-(trifluoromethyl)-2-hydroxy-2 H -chromenes with silyl enol ethers promoted by AlCl 3
作者: Liang ZhangXinjin LiZhongwei WangJingwei ZhaoJinjin WangJianwei HanShizheng Zhu
作者单位: 1College of Material Science and Technology, Shandong University of Science and Technology, Shandong, Qingdao 266590, China
2Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China
刊名: Tetrahedron, 2013, Vol.69 (37), pp.7975-7980
来源数据库: Elsevier Journal
DOI: 10.1016/j.tet.2013.07.004
关键词: ChromeneTrifluoromethylSilyl enol ethersNucleophilic substitutionLewis acid
英文摘要: Abstract(#br)An efficient and straightforward nucleophilic substitution reaction between 2-(trifluoromethyl)-2-hydroxy-2 H -chromenes and various silyl enol ethers promoted by Lewis acid has been studied. A series of novel 4-functionalized-2-trifluoromethyl-3-ethoxycarbonyl-4 H -chromenes were prepared in good yields under mild conditions.
全文获取路径: Elsevier  (合作)
影响因子:2.803 (2012)