The prospective evaluation of viral loads in patients with severe fever with thrombocytopenia syndrome
作者: Zhen-Dong YangJian-Gong HuQing-Bin LuChen-Tao GuoNing CuiWei PengLi-Yuan WangShu-Li QinHong-Yu WangPan-He ZhangXiao-Ai ZhangWei LiuWu-Chun Cao
作者单位: 1The 154 Hospital, Peoples Liberation Army, Xinyang 464000, PR China
2State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, PR China
3School of Public Health, Peking University, Beijing 100191, PR China
4Graduate School of Anhui Medical University, Hefei 230032, PR China
5The Shangcheng County People’s Hospital, Shangcheng, PR China
刊名: Journal of Clinical Virology, 2016, Vol.78 , pp.123-128
来源数据库: Elsevier Journal
DOI: 10.1016/j.jcv.2016.03.017
关键词: Severe fever with thrombocytopenia syndromeViral loadsProspective studySFTSVRT-PCR
原始语种摘要: Abstract(#br)Background(#br)Severe fever with thrombocytopenia syndrome (SFTS), caused by novel bunyavirus (SFTSV) is a potentially fatal disease that was first identified in China. Person to person transmission through contact with blood or body fluids was considered as an important infection route.(#br)Objectives(#br)The study is designed to investigate the longitudinal viral loads following SFTSV infection and to identify factors affecting viral shedding in SFTS patients.(#br)Methods(#br)A prospective, observational study was performed on 208 laboratory-confirmed SFTSV infected patients in Xinyang, Henan Province. Sequential serum samples were collected on admission and during the hospitalization for quantification of SFTSV RNA by real-time RT-PCR.(#br)Results(#br)The viral RNA was...
全文获取路径: Elsevier  (合作)
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影响因子:3.287 (2012)

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