An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids
作者: Shih-Hsin TuLi-Ching ChenYuan-Soon Ho
作者单位: 1Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
2Breast Medical Center, Taipei Medical University Hospital, Taipei, Taiwan
3Taipei Cancer Center, Taipei Medical University, Taipei, Taiwan
4Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
5Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
6Department of Laboratory Medicine, Taipei Medical University Hospital, Taipei, Taiwan
7Comprehensive Cancer Center of Taipei Medical University, Taipei, Taiwan
8School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan
刊名: Journal of Food and Drug Analysis, 2016
来源数据库: Elsevier Journal
DOI: 10.1016/j.jfda.2016.10.016
关键词: applecancer chemopreventionphloretintype 2 glucose transporter
英文摘要: Abstract(#br)The purpose of this review is to update and discuss key findings from in vitro and in vivo studies on apple and its biocompounds, with a special focus on its anticancer role. Several studies have proposed that apple and its extracts exhibit a variety of biological functions that may contribute to health benefits including beneficial effects against chronic heart and vascular disorders, respiratory and pulmonary dysfunction, diabetes, obesity, and cancer. In this review, we summarize the molecular mechanism(s) of various components in apple, as established in previous studies that indicated their growth-inhibitory effects in various cancer cell types. Moreover, an attempt is made to delineate the direction of future studies that could lead to the development of apple...
全文获取路径: Elsevier  (合作)
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