An increasing prevalence of recombinant GII norovirus in pediatric patients with diarrhea during 2010–2013 in China
作者: Qing-Bin LuDou-Dou HuangJin ZhaoHong-Yu WangXiao-Ai ZhangHong-Mei XuFen QuWei LiuWu-Chun Cao
作者单位: 1School of Public Health, Peking University, Beijing 100191, PR China
2State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, PR China
3Graduate School of Anhui Medical University, Hefei 230032, PR China
4Children’s Hospital, Chongqing Medical University, Chongqing 400014, PR China
5The PLA 302 hospital, Beijing 100039, PR China
刊名: Infection, Genetics and Evolution, 2015, Vol.31 , pp.48-52
来源数据库: Elsevier Journal
DOI: 10.1016/j.meegid.2015.01.008
关键词: NorovirusRecombinantDiarrheaChildrenChina
英文摘要: Abstract(#br)Noroviruses are the primary cause of acute nonbacterial gastroenteritis in humans and are responsible for nearly half of gastroenteritis cases globally. The norovirus strain variants have been circulating in underdeveloped regions in western China, where pediatric diarrhea acts as the major public health concern. The study aims to identify the epidemic genotypes of norovirus and explore their genetic characteristics in Chongqing, China. By performing a hospital-based surveillance from 2010 to 2013, we identified a significant shift of the predominant Norovirus strains in recent 4years in the studied area. The GII.4_Sydney_2012 and GII.12/GII.3 strains replaced GII.4_2006b and GII.4_NewOrleans_2009 to become the predominant genotypes, with the proportion of...
全文获取路径: Elsevier  (合作)
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影响因子:2.768 (2012)

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