Bloodstream infections in pediatric patients with acute leukemia: Emphasis on gram-negative bacteria infections
作者: Fu-Chun KuoShih-Min WangChing-Fen ShenYun-Ju MaTzong-Shiann HoJiann-Shiuh ChenChao-Neng ChengChing-Chuan Liu
作者单位: 1Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
2Department of Emergency Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
3Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan
刊名: Journal of Microbiology, Immunology and Infection, 2015
来源数据库: Elsevier Journal
DOI: 10.1016/j.jmii.2015.08.013
关键词: acute leukemiabloodstream infectionchildrengram-negative bacteria
英文摘要: Abstract(#br)Background/Purpose(#br)Acute leukemia is the most common pediatric hematological malignancy. Bloodstream infections (BSIs) are severe complications in these patients during chemotherapy. This study aims to explore clinical features, laboratory, and microbiological characteristics of BSIs in acute leukemic children.(#br)Methods(#br)Patients aged < 18 years, diagnosed with acute myeloid leukemia or acute lymphocytic leukemia with BSIs from January 2004 to December 2013 were enrolled. BSIs was defined as positive isolate(s) of blood culture and associated with clinical findings. Clinical presentations, demographic features, and microbiological findings were retrospectively reviewed.(#br)Results(#br)In total, 126 isolates of 115 episodes of BSIs were identified from 69 patients...
全文获取路径: Elsevier  (合作)
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