Amelioration of pancreatic and renal derangements in streptozotocin-induced diabetic rats by polyphenol extracts of Ginger ( Zingiber officinale ) rhizome
作者: Mutiu Idowu KazeemMusbau Adewunmi AkanjiMusa Toyin Yakubu
作者单位: 1Antidiabetic Drug Discovery Group, Department of Biochemistry, Faculty of Science, Lagos State University, PMB 0001, Lagos, Nigeria
2Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
刊名: Pathophysiology, 2015, Vol.22 (4), pp.203-209
来源数据库: Elsevier Journal
DOI: 10.1016/j.pathophys.2015.08.004
关键词: PolyphenolsPancreasKidneyStreptozotocinDiabetes
原始语种摘要: Abstract(#br)Free and bound polyphenol extracts of Zingiber officinale rhizome were investigated for their antidiabetic potential in the pancreatic and renal tissues of diabetic rats at a dose of 500mg/kg body weight. Forty Wistar rats were completely randomized into five groups: A–E consisting of eight animals each. Group A (control) comprises normal healthy animals and were orally administered 1.0mL distilled water on a daily basis for 42 days while group B–E were made up of 50mg/kg streptozotocin (STZ)-induced diabetic rats. Group C and D received 1.0mL 500mg/kg body weight free and bound polyphenol extracts respectively while group E received 1.0mL 0.6...
全文获取路径: Elsevier  (合作)

  • streptozotocin 链脲佐菌素
  • rhizome 根茎
  • diabetic 糖尿病患者
  • polyphenol 多元酚
  • extracts 摘记
  • pancreatic 胰的
  • renal 肾的
  • induced 感应的
  • glibenclamide 格列本脲
  • insulin 胰岛素