Processing of sentinel lymph nodes for detection of metastatic melanoma
作者: Victor G. PrietoSandra H. Clark
作者单位: 1From the Departments of Pathology and Dermatology, The University of Texas M. D. Anderson Cancer Center, Houston, TX.
刊名: Annals of Diagnostic Pathology, 2002, Vol.6 (4), pp.257-264
来源数据库: Elsevier Journal
DOI: 10.1053/adpa.2002.35400
原始语种摘要: Abstract(#br)Within the last years, evaluation of sentinel lymph nodes (SLN) has become the most popular method of early staging of several malignancies, including breast carcinoma and melanoma. Because SLN are reportedly the lymph nodes most likely to contain metastatic deposits, identification of such nodes allows pathologists to examine the tissue in a much more intense manner than with the usual lymphadenectomy specimens containing multiple lymph nodes. However, there is not a universally accepted standard protocol for pathologic processing of the SLN. Initially, the most popular protocols called for bisection of the SLN and examination of serial sections, with or without routinely performed immunohistochemistry. Lately, other protocols have been proposed to try to simplify the...
全文获取路径: Elsevier  (合作)
影响因子:0.975 (2012)