Evaluation of cardiac hyperthropy in spontaneous hypertensive rats using measures of left ventricular deformation and lvef of cardiac micropet imaging data
作者: A.I VeressB FengY YangJ.A WeissR.H HuesmanG.T Gullberg
作者单位: 1Department of Bioengineering, University of Utah, Salt Lake City, Utah, USA
2University of Massachusetts Medical Center, Worchester, MA, USA
3Department of Biomedical Engineering, University of California, Davis, California, USA
4Life Sciences Division, E. O. Lawrence Berkeley National Laboratory, Berkeley, California, USA
刊名: Journal of Nuclear Cardiology, 2004, Vol.11 (4), pp.S21-S22
来源数据库: Elsevier Journal
DOI: 10.1016/j.nuclcard.2004.06.069
原始语种摘要: Abstract(#br)Background: Assessment of regional heart wall deformation can provide quantitative information regarding ventricular wall function in congestive heart failure. In particular, mechanisms involving the progression of cardiac hypertrophy are being evaluated in rat models using measures of LVEF and 3D left ventricular deformation.(#br)Methods: PET data were acquired using the microPET II. A dose of 1 mCi of F-18-FDG was injected into normotensive Wistar Kyoto (WKY) rats and the same dose was injected into spontaneous hypertensive rats (SHR). The rats ranged in weight from 200 to 350 grams. For imaging a gated acquisition is used for one hour acquiring eight frames over the cardiac cycle of approximately 500–900 million total counts. LVEF was calculated using a method that does...
全文获取路径: Elsevier  (合作)
影响因子:2.847 (2012)