Prediction of non-sentinel lymph node involvement in breast cancer patients with a positive sentinel lymph node
作者: Anneleen ReyndersOlivier BrouckaertAnn SmeetsAnnouschka LaenenEmi YoshiharaFrederik PersynGiuseppe FlorisKarin LeunenFrederic AmantJulie SoensChantal Van OngevalPhilippe MoermanIgnace VergoteMarie-Rose ChristiaensGracienne StaelensKoen Van EygenAlain VannestePeter Van DamCecile ColpaertPatrick Neven
作者单位: 1Multidisciplinary Breast Center, KULeuven, University Hospitals, Herestraat 49, Belgium
2Department of Pathology, KULeuven, University Hospitals, Herestraat 49, Belgium
3Department of Radiology, KULeuven, University Hospitals, Herestraat 49, Belgium
4Multidisciplinary Breast Center, General Hospital Groeninge Kortrijk, President Kennedylaan 4, Belgium
5Department of Pathology, General Hospital Groeninge Kortrijk, President Kennedylaan 4, Belgium
6Multidisciplinary Breast Center, General Hospital Sint-Augustinus Wilrijk, Oosterveldlaan 24, Belgium
7Department of Pathology, General Hospital Sint-Augustinus Wilrijk, Oosterveldlaan 24, Belgium
刊名: The Breast, 2014, Vol.23 (4), pp.453-459
来源数据库: Elsevier Journal
DOI: 10.1016/j.breast.2014.03.009
关键词: Breast cancerSentinel lymph nodePredictionNon-sentinel lymph node involvementExternal validation
英文摘要: Abstract(#br)Completion axillary lymph node dissection (cALND) is the golden standard if breast cancer involves the sentinel lymph node (SLN). However, most non-sentinel lymph nodes (NSLN) are not involved, cALND has a considerable complication rate and does not improve outcome. We here present and validate our predictive model for positive NSLNs in the cALND if the SLN is positive.(#br)Consecutive early breast cancer patients from one center undergoing cALND for a positive SLN were included. We assessed demographic and clinicopathological variables for NSLN involvement. Uni- and multivariate analysis was performed. A predictive model was built and validated in two external centers.(#br)21.9% of 470 patients had at least one involved NSLN. In univariate analysis, seven variables were...
全文获取路径: Elsevier  (合作)
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影响因子:2.491 (2011)

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