Diagnostic value of plasma signal peptide-Cub-Egf domain-containing protein-1 (SCUBE-1) in an experimental model of acute ischemic stroke
作者: Suha TurkmenUmut EryigitYunus KaracaAhmet MenteseUzun Aysegul SumerEsin YulugNurhak AksutSibel GaziogluAbdulkadir Gunduz
作者单位: 1Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey
2Diyarbakır Selahaddin Eyyubi State Hospital, Department of Emergency Medicine, Diyarbakır, Turkey
3Karadeniz Technical University, Faculty of Medicine, Department of Biochemistry, Trabzon, Turkey
4Karadeniz Technical University, Faculty of Medicine, Department of Histology, Trabzon, Turkey
5Manisa State Hospital, Department of Emergency Medicine, Manisa, Turkey
6Karadeniz Technical University, Faculty of Medicine, Department of Neurology, Trabzon, Turkey
刊名: American Journal of Emergency Medicine, 2015, Vol.33 (2), pp.262-265
来源数据库: Elsevier Journal
DOI: 10.1016/j.ajem.2014.11.051
原始语种摘要: Abstract(#br)Objectives(#br)This study was intended to examine possible diagnostic value of plasma Signal Peptide-Cub-Egf domain-containing protein-1 (SCUBE1) levels in an experimental model of acute ischemic stroke.(#br)Methods(#br)Twenty-four female Sprague Dawley rats were divided into four groups. Blood and brain tissue specimens were collected immediately following artery ligation (control; Group 1), 1h after ligation (Group 2), 2h after ligation (Group 3) and 6h after ligation (Group 4). SCUBE1 levels were investigated in the serum specimens. The brain samples were examined histopathologically. Correlation analysis was performed between the values.(#br)Results(#br)Median SCUBE1 values were 1.75ng/ml in the...
全文获取路径: Elsevier  (合作)
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影响因子:1.704 (2012)

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