Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial
作者: Kypros H. NicolaidesArgyro SyngelakiLiona C. PoonCatalina de Paco MatallanaWalter PlasenciaFrancisca S. MolinaGemma PicciarelliNatasa TulEbru CelikTze Kin LauRoberto Conturso
作者单位: 1Harris Birthright Research Center for Fetal Medicine, King’s College, London, United Kingdom
2Department of Obstetrics and Gynecology, Hospital Universitario Virgen de La Arrixaca, Murcia, Spain
3Maternal Fetal Medicine Unit, Hospital Universitario Materno Infantil de Canarias, Las Palmas de Gran Canaria, Canary Islands, Spain
4Department of Obstetrics and Gynecology, University Hospital of Granada, Granada, Spain
5Department of Fetal Medicine, Medway Maritime Hospital, Gillingham, United Kingdom
6Department of Perinatology, Division of Obstetrics and Gynecology, University Medical Center Ljubljana, Slovenia
7Department of Obstetrics and Gynecology, Chinese University of Hong Kong, Hong Kong, China
8Department of Obstetrics and Gynecology, Ospedale Valduce, Como, Italy
刊名: American Journal of Obstetrics and Gynecology, 2016, Vol.214 (1), pp.3.e1-3.e9
来源数据库: Elsevier Journal
DOI: 10.1016/j.ajog.2015.08.051
关键词: Arabin pessarycervical lengthneonatal morbidityprematuritypreterm birthsonographic short cervixtwins
英文摘要: Background(#br)Preterm birth is the leading cause of neonatal death and handicap in survivors. Although twins are found in 1.5% of pregnancies they account for about 25% of preterm births. Randomized controlled trials in singleton pregnancies reported that the prophylactic use of progestogens, cervical cerclage and cervical pessary reduce significantly the rate of early preterm birth. In twin pregnancies, progestogens and cervical cerclage have been shown to be ineffective in reducing preterm birth.(#br)Objective(#br)The objective of this study was to test the hypothesis that the insertion of a cervical pessary in twin pregnancies would reduce the rate of spontaneous early preterm birth.(#br)Study Design(#br)This was a multicenter, randomized controlled trial in unselected twin...
全文获取路径: Elsevier  (合作)
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影响因子:3.877 (2012)

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