Fine Needle Aspiration Biopsy in Uveal Melanoma: Technique, Complications, and Outcomes
作者: Alexandre SellamLaurence DesjardinsRaymond BarnhillCorine PlancherBernard AsselainAlexia SavignoniGaelle PierronNathalie Cassoux
作者单位: 1Department of Ophthalmology, Institut Curie, Paris, France
2Department of Pathology, Institut Curie, Paris, France
3Department of Statistics, Institut Curie, Paris, France
4Department of Genetics, Institut Curie, Paris, France
5University Paris V Descartes, Paris, France
刊名: American Journal of Ophthalmology, 2016, Vol.162 , pp.28-34.e1
来源数据库: Elsevier Journal
DOI: 10.1016/j.ajo.2015.11.005
英文摘要: Purpose(#br)To report the technical aspects, complications, and outcomes concerning fine needle aspiration biopsy (FNAB) in uveal melanoma.(#br)Design(#br)Retrospective cohort study.(#br)Methods(#br)Patients with uveal melanoma who underwent transscleral or transvitreal FNAB at an ocular oncology center were retrospectively evaluated. FNAB was performed if the tumor was more than 5 mm in thickness. Array comparative genomic hybridization analysis was performed on biopsy samples with sufficient tissue. The main outcome measures were success (sample that gave a successful result for biomarker analysis) rate, complications, liver metastasis, and overall survival.(#br)Results(#br)There were 217 (114 male, 52%) consecutive study patients with a mean age of 56.7 (16–84) years. The mean...
全文获取路径: Elsevier  (合作)
影响因子:3.631 (2012)