Synthesis of 4-arylcoumarins via palladium-catalyzed arylation/cyclization of ortho -hydroxylcinnamates with diaryliodonium salts
作者: Yang YangJianwei HanXunshen WuShujia XuLimin Wang
作者单位: 1Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China
2Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai 200032, China
刊名: Tetrahedron Letters, 2015, Vol.56 (24), pp.3809-3812
来源数据库: Elsevier Journal
DOI: 10.1016/j.tetlet.2015.04.082
关键词: ArylationPalladiumCyclizationDiaryliodonium saltsCoumarin
英文摘要: Abstract(#br)The palladium-catalyzed arylation/cyclization of ortho -hydroxylcinnamate ester derivatives by using diaryliodonium(III) salts has been developed. With this method, 4-arylcoumarins were easily prepared in good to excellent yields under base-free conditions. Additionally, this protocol provided an efficient alternative for the preparation of related 4-arylated coumarin compounds which are useful in the access to 5-lipoxygenase inhibitors.
全文获取路径: Elsevier  (合作)
影响因子:2.397 (2012)

  • arylation 芳基化
  • catalyzed 催化的
  • palladium 
  • cyclization 环化
  • salts 盐类
  • Palladium 智慧女神雅典娜的神像
  • ortho 垂直