Screening individuals with intracranial aneurysms for abdominal aortic aneurysms is cost-effective based on estimated coprevalence
作者: Benjamin Z. BallBoxiang JiangPrachi MehndirattaGeorge J. StukenborgGilbert R. UpchurchJames F. MeschiaBradford B. WorrallAndrew M. Southerland
作者单位: 1Department of Neurology, University of Virginia, Charlottesville, Va
2Department of Public Health Sciences, University of Virginia, Charlottesville, Va
3Department of Surgery, University of Virginia, Charlottesville, Va
4Department of Neurology, Mayo Clinic, Jacksonville, Fla
刊名: Journal of Vascular Surgery, 2016, Vol.64 (3), pp.811-818.e3
来源数据库: Elsevier Journal
DOI: 10.1016/j.jvs.2016.05.065
英文摘要: Abstract(#br)Objective(#br)Aneurysm rupture is a major cause of morbidity and mortality, and evidence suggests shared risk for both abdominal aortic aneurysms (AAAs) and intracranial aneurysms (IAs). We hypothesized that screening for AAA in patients with known IA is cost-effective.(#br)Methods(#br)We used a decision tree model to compare costs and outcomes of AAA screening vs no screening in a hypothetical cohort of patients with IA. We measured expected outcomes using quality-adjusted life-years (QALYs) and the incremental cost-effectiveness ratio (ICER). We performed a Monte Carlo simulation and additional sensitivity analyses to assess the effects of ranging base case variables on model outcomes and identified thresholds where a decision alternative dominated the model (both less...
全文获取路径: Elsevier  (合作)
影响因子:2.879 (2012)