The effects of hypothermia on human left ventricular contractile function during cardiac surgery
作者: Michael E LewisAbdhul-Hakam Al-KhalidiJohn N TownendJohn CooteRobert S Bonser
作者单位: 1Department of Cardiothoracic Surgery, Queen Elizabeth Hospital, Birmingham, United Kingdom
2Department of Physiology, University of Birmingham, Birmingham, United Kingdom
3Department of Cardiovascular Medicine, Queen Elizabeth Hospital, Birmingham, United Kingdom
刊名: Journal of the American College of Cardiology, 2002, Vol.39 (1), pp.102-108
来源数据库: Elsevier Journal
DOI: 10.1016/S0735-1097(01)01694-1
原始语种摘要: Abstract(#br)Objectives(#br)We investigated the interaction of heart rate (HR), temperature and contractility using a validated load independent method.(#br)Background(#br)Temperature manipulation is an integral part of cardiac surgery, and postoperative hypothermia is extremely common. Myocardial contraction is a series of enzymatic and physico-chemical reactions that may be differentially affected by temperature.(#br)Methods(#br)Ten patients undergoing coronary artery bypass grafting were studied during moderately hypothermic cardiopulmonary bypass. After conduit procurement and heparinization but before grafting, the patient was placed on cardiopulmonary bypass and rewarmed to 37°C, and the left ventricle (LV) was instrumented with a conductance catheter allowing continuous pressure...
全文获取路径: Elsevier  (合作)
影响因子:14.086 (2012)