The effects of bacterial endotoxin on cochlear function and the blood labyrinth barrier
作者: Steven K. JuhnBo-Hyung KimPatricia SchachernVladimir TsuprunGeorge L. Adams
作者单位: 1Minneapolis MN; Chung-ju South Korea; Minneapolis MN; Minneapolis MN; Minneapolis MN
刊名: Otolaryngology - Head and Neck Surgery, 2004, Vol.131 (2), pp.P145-P145
来源数据库: Elsevier Journal
DOI: 10.1016/j.otohns.2004.06.237
原始语种摘要: Abstract(#br)Problem: Middle ear infection, one of the most common childhood diseases, has the potential to cause inner ear pathology, resulting in hearing loss or communication disorders. Specific mechanisms responsible for inner ear dysfunction due to otitis media are not clearly understood. It appears that inflammatory mediators and bacterial toxins pass through the round window membrane resulting in structural and biochemical changes in the inner ear leading to auditory dysfunction. This study was undertaken to examine auditory function and the blood labyrinthine barrier in the lateral wall of the cochlea, after bacterial endotoxin administration.(#br)Methods: Chinchillas weighing 400 to 500 g were injected intravenously with 1 ml of 10 mg/ml LPS (LPS, Sigma Co, derived from...
全文获取路径: Elsevier  (合作)
影响因子:1.625 (2012)