Potential risk of monochorionic dizygotic twin blastocyst formation associated with early laser zona dissection of group cultured embryos
作者: Mitchel C. SchieweJohn B. WhitneyRobert E. Anderson
作者单位: 1Southern California Institute for Reproductive Sciences, Newport Beach, California
2Southern California Center for Reproductive Medicine, Newport Beach, California
刊名: Fertility and Sterility, 2015, Vol.103 (2), pp.417-421
来源数据库: Elsevier Journal
DOI: 10.1016/j.fertnstert.2014.11.009
关键词: Blastocystsin vitro derivedmonochorionic dizygotic twins
英文摘要: Objective(#br)To document the risk of in vitro monochorionic dizygotic twin formation in the implementation of a program of blastocyst biopsy with preimplantation genetic screening (PGS).(#br)Design(#br)Case report.(#br)Setting(#br)Private infertility laboratory.(#br)Patient(s)(#br)Prospective PGS patients with intracytoplasmic sperm injection–derived, group-cultured blastocysts over a 3-year period.(#br)Intervention(s)(#br)Group culture in Global medium (Life Global) to optimize blastocyst formation of zygotes produced for blastocyst biopsy for PGS (n ≤ 8 embryos/25 μL droplet), and laser zona dissection (LZD) of all day-3 cleaved embryos to promote pre-expansion trophectodermal extrusion at the blastocyst stage (i.e., premature hatching).(#br)Main Outcome Measure(s)(#br)Blastocyst...
全文获取路径: Elsevier  (合作)
影响因子:4.174 (2012)