Neoadjuvant chemotherapy followed by large cone resection as fertility-sparing therapy in stage IB cervical cancer
作者: Rawand SalihiKarin LeunenErik Van LimbergenPhilippe MoermanPatrick NevenIgnace Vergote
作者单位: 1Department of Gynaecologic Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven, Belgium
2Department of Radiotherapy-Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven, Belgium
3Department of Pathology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven, Belgium
刊名: Gynecologic Oncology, 2015, Vol.139 (3), pp.447-451
来源数据库: Elsevier Journal
DOI: 10.1016/j.ygyno.2015.05.043
关键词: Fertility sparing surgeryCervical cancerNeoadjuvant chemotherapyCone resection
原始语种摘要: Abstract(#br)Background(#br)Standard treatment of cervical cancer FIGO stage IB1 is a radical hysterectomy with pelvic lymphadenectomy. As the number of patients with a preserved fertility wish has increased, the need for fertility sparing surgery emerges. In this study we discuss 11 patients with cervical carcinoma stage IB treated with neoadjuvant chemotherapy followed by large cone resection.(#br)Methods(#br)In this retrospective study we included 10 patients with FIGO stage IB1 and 1 patient with IB2 cervical cancer, who first received a pelvic lymphadenectomy followed by neoadjuvant chemotherapy and conization. Paclitaxel–ifosfamide–carboplatin or a combination of paclitaxel–carboplatin was used as neoadjuvant chemotherapy.(#br)Results(#br)Complete response after chemotherapy was...
全文获取路径: Elsevier  (合作)
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影响因子:3.929 (2012)

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