Behavioral toxicology of cognition: Extrapolation from experimental animal models to humans
作者: Merle G. PauleLeonard GreenJoel MyersonMaria AlvaradoJocelyne BachevalierJay S. SchneiderSusan L. Schantz
作者单位: 1Divison of Neurotoxicology, National Center for Toxicological Research, FDA, Jefferson, AR, United States
2Department of Psychology, Washington University, St. Louis, MO, United States
3Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States
4Department of Psychology, Emory University, Atlanta, GA, United States
5Dept. of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, United States
6Comparative Biosciences, Pharmacology/Toxicology Division, College of Veterinary Medicine, University of Illinois, Urbana, IL, United States
刊名: Neurotoxicology and Teratology, 2012, Vol.34 (2), pp.263-273
来源数据库: Elsevier Journal
DOI: 10.1016/
关键词: Behavioral toxicologyNonhuman primateMonkeyRodentTranslational neuroscience
原始语种摘要: Abstract(#br)A variety of behavioral instruments are available for assessing important aspects of cognition in both animals and humans and, in many cases, the same instruments can be used in both. While nonhuman primates are phylogenetically closest to humans, rodents, pigeons and other animals also offer behaviors worthy of note. Delay Discounting procedures are as useful as any in studies of impulsivity and may have utility in shedding light on processes associated with drug abuse. Specific memory tests such as Visual Paired Comparisons tasks (similar to the Fagan test of infant intelligence) can be modified to allow for assessment of different aspects of memory such as spatial memory. Use of these and other specific memory tasks can be used to directly monitor aspects of cognitive...
全文获取路径: Elsevier  (合作)
影响因子:3.181 (2012)

  • cognition 认识
  • flexibility 柔顺性
  • toxicology 毒物学
  • diminishing 衰减
  • working 开采
  • often 往往
  • function 函数
  • cognitive 修]认知[识
  • assess 查定
  • their 他们的