Single wavelength light-mediated, synergistic bimodal cancer photoablation and amplified photothermal performance by graphene/gold nanostar/photosensitizer theranostics
作者: Chunhui WuDan LiLianhui WangXiaotian GuanYuan TianHong YangShun LiYiyao Liu
作者单位: 1Department of Biophysics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China
2Center for Information in BioMedicine, University of Electronic Science and Technology of China, Chengdu 610054, PR China
3Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, PR China
刊名: Acta Biomaterialia, 2017, Vol.53 , pp.631-642
来源数据库: Elsevier Journal
DOI: 10.1016/j.actbio.2017.01.078
关键词: Graphene oxideGold nanostarPhotothermal effectPhotodynamic therapyPhotothermal imaging
原始语种摘要: Abstract(#br)Light-triggered nanotheranostics opens a fascinating but challenging avenue to achieve simultaneous and highly efficient anticancer outcomes for multimodal therapeutic and diagnostic modalities. Herein, a multifunctional phototheranostics based on a photosensitizer-assembled graphene/gold nanostar hybrid (GO/AuNS-PEG) was developed for cancer synergistic photodynamic (PDT) and photothermal therapy (PTT) as well as effective photothermal imaging. The stable and biocompatible GO/AuNS-PEG composite displayed a high photothermal conversion efficiency due to the enhanced optical absorbance of both graphene and gold nanostars in the near-infrared (NIR) range. By tuning the absorption wavelength of GO/AuNS-PEG to that of Chlorin e6 (Ce6), GO/AuNS-PEG/Ce6 completely eliminated the...
全文获取路径: Elsevier  (合作)
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来源刊物:
影响因子:5.093 (2012)

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关键词翻译
关键词翻译
  • light 
  • wavelength 波长
  • bimodal 双峰的
  • amplified verification扩大核查
  • performance 性能
  • effect 效应
  • oxide 氧化物
  • imaging 图像形成
  • synergistic 协同的
  • cancer 癌症