Rapid Resolution of Nitrofurantoin-Induced Interstitial Lung Disease
作者: Miguel Ángel Núñez ViejoAna Fernández MontesJavier Velasco MontesJosé Javier Gómez-RománCarmen García IbarbiaJosé Luis Hernández Hernández
作者单位: 1Departamento de Medicina Interna, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain
2Departamento de Anatomía Patológica, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain
刊名: Archivos de Bronconeumología (Internet), 2009, Vol.45 (7), pp.352-355
来源数据库: Elsevier Journal
DOI: 10.1016/S1579-2129(09)72437-1
关键词: NitrofurantoinInterstitial lung diseaseTransbronchial biopsyCorticosteroidsNitrofurantoínaEnfermedad pulmonar intersticialBiopsia transbronquialCorticoides
原始语种摘要: Abstract(#br)We report the case of a 40-year-old woman diagnosed with interstitial lung disease due to long-term nitrofurantoin therapy. Despite severely distorted bronchiolar architecture and honeycombing confirmed by computed tomography of the thorax, transbronchial biopsy showed a pattern of acute/subacute interstitial pneumonitis and the symptoms and radiographic findings disappeared within 1 month after administration of prednisone. This case shows that nitrofurantoin-induced lung disease may run a benign course and respond favorably to corticosteroids, even when there is radiographic evidence of established lung fibrosis. Transbronchial biopsy might be useful for assessing the reversibility of pulmonary lesions associated with nitrofurantoin.(#br)Resumen(#br)Presentamos el caso de...
全文获取路径: Elsevier  (合作)
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影响因子:1.372 (2012)

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