Comparison of paired serum and lithium heparin plasma samples for the measurement of serum amyloid A in horses using an automated turbidimetric immunoassay
作者: Judith HowardClaudia Graubner
作者单位: 1Clinical Diagnostic Laboratory, Department of Veterinary Clinical Medicine, Vetsuisse Faculty, University of Berne, Länggassstrasse 124, CH-3012 Bern, Switzerland
2Swiss Institute of Equine Medicine (ISME), Vetsuisse Faculty, University of Berne, Länggassstrasse 124, CH-3012 Bern, Switzerland
刊名: The Veterinary Journal, 2014, Vol.199 (3), pp.457-460
来源数据库: Elsevier Journal
DOI: 10.1016/j.tvjl.2013.12.007
关键词: Acute phase proteinsAnticoagulant effectsHorsePlasmaSerum amyloid A
英文摘要: Abstract(#br)This study aimed to evaluate whether equine serum amyloid A (SAA) concentrations could be reliably measured in plasma with a turbidimetric immunoassay previously validated for equine SAA concentrations in serum. Paired serum and lithium-heparin samples obtained from 40 horses were evaluated. No difference was found in SAA concentrations between serum and plasma using a paired t test ( P =0.48). The correlation between paired samples was 0.97 (Spearman’s rank P <0.0001; 95% confidence interval 0.95–0.99). Passing-Bablok regression analyses revealed no differences between paired samples. Bland–Altman plots revealed a positive bias in plasma compared to serum but the difference was not considered...
全文获取路径: Elsevier  (合作)
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影响因子:2.424 (2012)

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