Utility of inflammatory markers in predicting the aetiology of pneumonia in children
作者: Mohamed A. ElemraidStephen P. RushtonMatthew F. ThomasDavid A. SpencerAndrew R. GenneryJulia E. Clark
作者单位: 1Department of Paediatric Infectious Disease and Immunology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK
2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE1 7RU, UK
3Biological, Clinical and Environmental Systems Modelling Group, School of Biology, Newcastle University, Newcastle upon Tyne NE1 7RU, UK
4Department of Respiratory Paediatrics, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK
5Department of Paediatric Infectious Disease, Royal Children's Hospital, Brisbane, Queensland 4029, Australia
刊名: Diagnostic Microbiology & Infectious Disease, 2014, Vol.79 (4), pp.458-462
来源数据库: Elsevier Journal
DOI: 10.1016/j.diagmicrobio.2014.04.006
关键词: C-reactive proteinNeutrophilsPaediatricsPneumoniaPredictionWhite cells
原始语种摘要: Abstract(#br)We aimed to investigate the diagnostic value of applying cut-off levels of inflammatory markers and to develop a prediction model for differentiation between bacterial and viral infections in paediatric community-acquired pneumonia based on C-reactive protein (CRP), neutrophil, and white cell counts (WCC). Amongst 401 children, those with bacterial pneumonia were older than those with viral pneumonia ( P <0.001). Compared to viral, bacterial infections had a higher median CRP level ( P <0.001), whereas WCC and neutrophil count were not different. Bacterial infections were associated with higher CRP >80 mg/L than viral infections ( P =0.001), but levels <20 mg/L...
全文获取路径: Elsevier  (合作)
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