Preterm Birth and Adolescent Social Functioning–Alterations in Emotion-Processing Brain Areas
作者: Elaine HealyAbraham ReichenbergKie Woo NamMatthew P.G. AllinMuriel WalsheLarry RifkinSir Robin M. MurrayChiara Nosarti
作者单位: 1Department of Psychosis Studies, Institute of Psychiatry, King's Health Partners, King's College London, London, United Kingdom
2Lucena Clinic Child and Adolescent Mental Health Service, Rathgar, Dublin, Ireland
刊名: The Journal of Pediatrics, 2013, Vol.163 (6), pp.1596-1604
来源数据库: Elsevier Journal
DOI: 10.1016/j.jpeds.2013.08.011
英文摘要: Objective(#br)To investigate the relationship between preterm birth, adolescent, and adult psychosocial outcomes, and alterations in gray matter volume.(#br)Study design(#br)Individuals (n = 73) born at <33 weeks of gestation (very preterm) and 49 controls completed the Child Behavior Checklist (CBCL) at age 15 years to identify ‘social immaturity’ (SI) cases. Voxel-based morphometry was used to investigate gray matter volumes according to CBCL-SI ‘caseness.’ The Clinical Interview Schedule-Revised (CIS-R) was administered at age 19 years.(#br)Results(#br)Very preterm adolescents were almost 4 times more likely to reach CBCL-SI ‘caseness’ compared with controls. Ex-preterm SI ‘cases’ had increased gray matter volume in the fusiform gyrus bilaterally (Talairach coordinates: x = 60, y =...
全文获取路径: Elsevier  (合作)
影响因子:4.035 (2012)