Increased percentage of Th17 cells in peritoneal fluid is associated with severity of endometriosis
作者: Marek GogaczIzabela WinklerAgnieszka Bojarska-JunakJacek TabarkiewiczAndrzej SemczukTomasz RechbergerAneta Adamiak
作者单位: 1Oncology Centre of the Lublin, Jaczewski Street 7, 20-090 Lublin, Poland
2II Department of Gynecology, Lublin Medical University, Jaczewski Street 8, 20-954 Lublin, Poland
3Department of Clinical Immunology, Lublin Medical University, Chodźki Street 4a, 20-093 Lublin, Poland
4Centre for Innovative Research in Medical and Natural Sciences, Medical Faculty of University of Rzeszów, Warzywna Street, 35-959 Rzeszów, Poland
刊名: Journal of Reproductive Immunology, 2016, Vol.117 , pp.39-44
来源数据库: Elsevier Journal
DOI: 10.1016/j.jri.2016.04.289
关键词: EndometriosisPeripheral bloodPeritoneal fluidTh17 cells
原始语种摘要: Abstract(#br)Aim(#br)Th17 cells are a newly discovered T helper lymphocyte subpopulation, producing interleukin IL-17. Th17 cells are present in blood and peritoneal fluid (PF) at different stages of endometriosis. We aim to establish their potential importance in the pathogenesis and clinical features of the disease.(#br)Methods(#br)The percentage of Th17 cells among T helper lymphocytes was determined in the PF and peripheral blood (PB) of patients with endometriosis and in the control group by flow cytometry using monoclonal antibodies: anti-CD-4-FITC, anti-CD-3-PE/Cy5, and anti-IL-17A-PE.(#br)Results(#br)Th17 percentage is increased in PF in comparison with PB in both endometriotic patients and in the control group. In severe endometriosis, the percentage of Th17 cells in PF was...
全文获取路径: Elsevier  (合作)
影响因子:2.342 (2012)