Single nucleotide polymorphisms as markers of genetic susceptibility for oral potentially malignant disorders risk: Review of evidence to date
作者: Krithiga ShridharAastha AggarwalGagandeep Kaur WaliaSmriti GulatiA.V. GeethaD. PrabhakaranPreet K. DhillonPreetha Rajaraman
作者单位: 1Centre for Chronic Conditions and Injuries, Public Health Foundation of India, Haryana, India
2Centre for Chronic Disease Control, Haryana, India
3London School of Hygiene and Tropical Medicine, London, United Kingdom
4Centre for Global Health, National Cancer Institute, Bethesda, USA
刊名: Oral Oncology, 2016, Vol.61 , pp.146-151
来源数据库: Elsevier Journal
DOI: 10.1016/j.oraloncology.2016.08.005
关键词: Oral potentially malignant disordersSusceptibilitySNPPolymorphisms
英文摘要: Summary(#br)Background(#br)Oral cancers are preceded by oral potentially malignant disorders (OPMD). Understanding genetic susceptibility for OPMD risk could provide an opportunity for risk assessment of oral cancer through early disease course. We conducted a review of single nucleotide polymorphism (SNP) studies for OPMD risk.(#br)Methods(#br)We identified all relevant studies examining associations of SNPs with OPMD (leukoplakia, erythroplakia and oral sub-mucous fibrosis) conducted world-wide between January, 2000 and February, 2016 using a combined keyword search on PubMed. Of these, 47 studies that presented results as odds ratios and 95% CI were considered for full review.(#br)Results(#br)The majority of eligible studies that explored candidate gene associations for OPMD were small...
全文获取路径: Elsevier  (合作)
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影响因子:2.695 (2012)

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