Updates in the diagnosis of combined hepatocellular-cholangiocarcinoma
作者: Amedeo SciarraYoung Nyun ParkChristine Sempoux
作者单位: 1Service of Clinical Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, 1011, Lausanne, Switzerland
2Department of Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea
刊名: Human Pathology, 2020, Vol.96 , pp.48-55
来源数据库: Elsevier Journal
DOI: 10.1016/j.humpath.2019.11.001
关键词: Combined hepatocellular-cholangiocarcinomaPrimary liver carcinomaHepatocellular carcinomaCholangiocarcinomaCholangiolocarcinoma
英文摘要: Summary(#br)Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare primary liver carcinoma showing variable degrees of differentiation toward hepatocellular and cholangiocellular carcinoma. Its great heterogeneity in term of morphology, immunophenotype, molecular, radiological and clinical features represents a challenge still to overcome. The multidisciplinary 2018 International Consensus on the nomenclature of cHCC-CCA allowed to define key issues of this entity. Here we review the historical controversies of cHCC-CCA, resume the key elements of the 2018 consensus, now incorporated in the 2019 WHO classification, and propose a short survival guide to help surgical pathologists facing cHCC-CCA in their routine workup.
全文获取路径: Elsevier  (合作)
影响因子:2.843 (2012)

  • hepatocellular 肝细胞性的
  • carcinoma 癌症
  • liver 
  • combined 组合
  • diagnosis 特镇述