Thermo/photo dual-crosslinking chitosan-gelatin methacrylate hydrogel with controlled shrinking property for contraction fabrication
作者: Xin LuoYidan LiuJianhui PangShichao BiZhongzheng ZhouZhe LuChao FengXiguang ChenMing Kong
作者单位: 1College of Marine Life Science, Ocean University of China, 5 Yushan Road, 266003, Qingdao, China
2Qingdao National Laboratory for Marine Science and Technology, China
刊名: Carbohydrate Polymers, 2020, Vol.236
来源数据库: Elsevier Journal
DOI: 10.1016/j.carbpol.2020.116067
关键词: Photo/thermo dual-crosslinkingControlled shrinking propertyMethacrylated hydroxybutyl chitosanGelatin metharylateContraction fabrication
原始语种摘要: Abstract(#br)Stimuli-responsive gel volume variation is reversible and has shown promising applications, which may be potential for contraction or expansion fabrication, generating shrinking or swelling volume of the original. In this study, a thermo/photo dual-crosslinking hydrogel is prepared with methacrylated hydroxylbutyl chitosan (MHBC) and gelatin methacrylate (GelMA). The M/G hydrogel undergoes sol-gel phase transition under room temperature and shrinking deformation upon elevating temperature. Besides nontoxicity and biodegradability, dual crosslink endowed the composite hydrogel with strengthened and tunable mechanical property, controlled and repeatable contraction property in response to temperature elevation from 25 ℃ to 37 ℃, and enhanced cell adhesion in 3D culture. These...
全文获取路径: Elsevier  (合作)
影响因子:3.479 (2012)

  • hydrogel 水凝胶
  • chitosan 壳聚糖
  • crosslinking 交联
  • gelatin 
  • shrinking 收缩
  • controlled 受控
  • fabrication 制造
  • methacrylate 甲基丙烯酸酯
  • property 所有权
  • potential