Environmental temperature and human epigenetic modifications: A systematic review
环境温度与人类表观遗传修饰的系统评价
作者: Rongbin XuShuai LiShuaijun GuoQi ZhaoMichael J. AbramsonShanshan LiYuming Guo
作者单位: 1Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, 3004, Australia
2Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, 3010, Australia
3Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK
4Centre for Community Child Health, Murdoch Children’s Research Institute, Royal Children’s Hospital, Melbourne, VIC, 3052, Australia
刊名: Environmental Pollution, 2020, Vol.259
来源数据库: Elsevier Journal
DOI: 10.1016/j.envpol.2019.113840
关键词: EpigeneticsTemperatureClimate changeEpidemiologySystematic review
英文摘要: Abstract(#br)The knowledge about the effects of environmental temperature on human epigenome is a potential key to understand the health impacts of temperature and to guide acclimation under climate change. We performed a systematic review on the epidemiological studies that have evaluated the association between environmental temperature and human epigenetic modifications. We identified seven original articles on this topic published between 2009 and 2019, including six cohort studies and one cross-sectional study. They focused on DNA methylation in elderly people (blood sample) or infants (placenta sample), with sample size ranging from 306 to 1798. These studies were conducted in relatively low temperature setting (median/mean temperature: 0.8–13 °C), and linear models were used to...
全文获取路径: Elsevier  (合作)
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影响因子:3.73 (2012)

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关键词翻译
关键词翻译
  • systematic 有系统的
  • epigenetic 后成的
  • temperature 温度
  • review 复审
  • human 人的