Gut Microbial Dysbiosis in the Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Case-Control Studies
作者: Lin WangNuha AlammarRajdeep SinghJulie NanavatiYiran SongRahul ChaudharyGerard E. Mullin
刊名: Journal of the Academy of Nutrition and Dietetics, 2020, Vol.120 (4), pp.565-586
来源数据库: Elsevier Journal
DOI: 10.1016/j.jand.2019.05.015
关键词: Irritable bowel syndromeGut microbiomeDysbiosisBifidobacteriaLactobacillus
英文摘要: Abstract(#br)Background(#br)Irritable bowel syndrome (IBS) is the most common functional digestive condition in the industrialized world. The gut microbiota plays a key role in disease pathogenesis.(#br)Objective(#br)A systematic review and meta-analysis on case–control studies was conducted to determine whether there is gut microbial dysbiosis in participants with IBS in comparison with healthy controls and, if so, whether the dysbiosis pattern differs among IBS subtypes and geographic regions.(#br)Methods(#br)This review was conducted and reported according to the MOOSE (Meta-Analysis of Observational Studies in Epidemiology) 2000 and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2009 guidelines. Research articles published up to May 9, 2018 were identified...
全文获取路径: Elsevier  (合作)

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