A review of bioselenol-specific fluorescent probes: Synthesis, properties, and imaging applications
生物硒醇特异性荧光探针综述:合成、性质和成像应用
作者: Yuning LiuXiaohui FengYanan YuQingyu ZhaoChaohua TangJunmin Zhang
作者单位: 1State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China
2Scientific Observing and Experiment Station of Animal Genetic Resources and Nutrition in North China of Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China
刊名: Analytica Chimica Acta, 2020, Vol.1110 , pp.141-150
来源数据库: Elsevier Journal
DOI: 10.1016/j.aca.2020.03.027
关键词: SeleniumBioselenolFluorescent probeSelenocysteineThioredoxin reductaseHydrogen selenide
英文摘要: Abstract(#br)Bioselenols are important substances for the maintenance of physiological balance and offer anticancer properties; however, their causal mechanisms and effectiveness have not been assessed. One way to explore their physiological functions is the in vivo detection of bioselenols at the molecular level, and one of the most efficient ways to do so is to use fluorescent probes. Various types of bioselenol-specific fluorescent probes have been synthesized and optimized using chemical simulations and by improving biothiol fluorescent probes. Here, we review recent advances in bioselenol-specific fluorescent probes for selenocysteine (Sec), thioredoxin reductase (TrxR), and hydrogen selenide (H 2 Se). In particular, the molecular design principles of different types of bioselenols,...
全文获取路径: Elsevier  (合作)
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影响因子:4.387 (2012)

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关键词翻译
关键词翻译
  • fluorescent 萤光的
  • probes 探针
  • properties 道具
  • specific 
  • imaging 图像形成
  • applications 应用程序
  • review 复审