UK national cohort of anal cancer treated with intensity-modulated radiotherapy: One-year oncological and patient-reported outcomes
作者: A. GilbertK. DrinkwaterL. McParlandR. AdamsR. Glynne-JonesM. HarrisonM.A. HawkinsD. Sebag-MontefioreD.C. GilbertR. Muirhead
作者单位: 1University of Leeds, Leeds Cancer Centre, St. James's University Hospital, Leeds, UK
2The Royal College of Radiologists, London, UK
3Leeds Clinical Trials Research Unit, Worsley Building, University of Leeds, Leeds, UK
4Cardiff University - Centre for Trials Research and Velindre Cancer Centre, Cardiff, UK
5Mount Vernon Centre for Cancer Treatment, Mount Vernon Hospital, Rickmansworth Road, Northwood, UK
6CRUK MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK
7Sussex Cancer Centre, Royal Sussex County Hospital, Eastern Road, Brighton, UK
8Oxford University Hospitals NHS Trust, Department of Oncology, Churchill Hospital, Oxford, UK
刊名: European Journal of Cancer, 2020, Vol.128 , pp.7-16
来源数据库: Elsevier Journal
DOI: 10.1016/j.ejca.2019.12.022
关键词: Anal cancerPatient-reported outcomesIntensity-modulated radiotherapy
英文摘要: Abstract(#br)Background(#br)Concurrent chemoradiotherapy is the standard treatment for anal cancer. Following national UK implementation of intensity-modulated radiotherapy (IMRT), this prospective, national cohort evaluates the one-year oncological outcomes and patient-reported toxicity outcomes (PRO) after treatment.(#br)Materials and methods(#br)A national cohort of UK cancer centers implementing IMRT was carried out between February to July 2015. Cancer centers provided data on oncological outcomes, including survival, and disease and colostomy status at one-year. EORTC-QLQ core (C30) and colorectal (CR29) questionnaires were completed at baseline and one-year followup. The PRO scores at baseline and one year were compared.(#br)Results(#br)40 UK Cancer Centers returned data with a...
全文获取路径: Elsevier  (合作)
影响因子:5.061 (2012)

  • radiotherapy 放射线疗法
  • modulated 巳的
  • cohort 伙伴
  • intensity 强度
  • treated 加工的
  • reported 报告的
  • national 国家的
  • patient 有耐性的
  • cancer 癌症