Microfabricated stem cell targeted differentiation systems
作者: Fang YeZhiqiang YanHaoqing ZhangHonglong ChangPavel Neuzil
作者单位: 1Northwestern Polytechnical University, School of Mechanical Engineering, Department of Microsystem Engineering, 127 West Youyi Road, Xi'an, Shaanxi, 710072, PR China
2Central European Institute of Technology, Brno University of Technology, Purkyňova 123, 612 00 Brno, Czech Republic
刊名: Trends in Analytical Chemistry, 2020, Vol.126
来源数据库: Elsevier Journal
DOI: 10.1016/j.trac.2020.115858
英文摘要: Abstract(#br)Recently, there has been a boom in stem cell research for various applications in biomedical engineering, regenerative medicine, tissue engineering, drug discovery, and artificial organs. It is crucial to maintain a well-controlled environment for stem cell culturing and subsequent differentiation. In this review, we discussed microfluidic devices, overcoming the limitations of conventional cell culture methods to provide new opportunities for stem cell research. We particularly debated methods used for stem cell differentiation into osteogenic, neural, and endothelial cells with respect to microfluidic systems. We concluded our review of microfluidic device-based stem cell targeted differentiation with an overview of the possibilities that this cutting-edge technology could...
全文获取路径: Elsevier  (合作)
影响因子:6.351 (2012)

  • targeted 对准目标的
  • systems 系统科学与软件