Detection of mutant genes with different types of biosensor methods
作者: Xiaohui LuMingxuan CuiQicheng YiAmin kamrani
作者单位: 1School of Earth Science and Engineering, Ministry of Education Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, Hohai University, Nanjing, 210098, China
2Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran
3Student's Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
刊名: Trends in Analytical Chemistry, 2020, Vol.126
来源数据库: Elsevier Journal
DOI: 10.1016/j.trac.2020.115860
关键词: BiosensorsGenosensorsPiezoelectric sensorPoint mutationGenes
英文摘要: Abstract(#br)Mutation is a permanent alteration in the sequence of genomic DNA which its integrity and stability is crucial for all living organism. Recognition of these mutations gives the opportunity to improve the therapeutic of these diseases. The most of detection techniques for point mutations are based on PCR. Despite being highly sensitive, PCR based approaches are suffering from amplification errors caused by mispriming. A biosensor as an analytical device measures biological or chemical reactions, through converting them into electrical signals. Biosensors that detect DNA molecules as the analyte are called genosensors or DNA biosensors. Different types of biosensors and also various piezoelectric sensors such as QCM (quartz crystal microbalance), SAW (Surface Acoustic Wave)...
全文获取路径: Elsevier  (合作)
影响因子:6.351 (2012)

  • mutant 突变体
  • different 不相同的
  • biosensor 生物传感器生物感测器