Progesterone receptor membrane component 1 (PGRMC1)-mediated progesterone effect on preimplantation development of in vitro produced porcine embryos
孕酮受体膜组分1 ( PGRMC1 )介导的孕酮对体外培养猪胚胎植入前发育的影响
作者: Man Ho ChoSeung-Hun KimDong-Kyung LeeMingyun LeeChang-Kyu Lee
作者单位: 1Department of Agricultural Biotechnology, Animal Biotechnology Major, Research Institute of Agriculture and Life Science, Seoul National University, Seoul, 08826, Republic of Korea
2Designed Animal & Transplantation Research Institute, Institute of Green Bio Science and Technology, Seoul National University, Gangwon-do, 25354, Republic of Korea
刊名: Theriogenology, 2020, Vol.147 , pp.39-49
来源数据库: Elsevier Journal
DOI: 10.1016/j.theriogenology.2020.02.013
关键词: ProgesteroneProgesterone receptorIn vitro embryo productionPigBlastocyst
英文摘要: Abstract(#br)Progesterone is a steroid hormone well known for its significant role in the reproduction process of mammals. Numerous studies have reported on the regulation of progesterone during implantation, pregnancy and parturition, but there are fewer studies on progesterone in relation to the early stages of embryo development. In the present study, we investigated the effects of progesterone during the development of in vitro produced porcine embryos. First, gene expression of various progesterone receptors in the in vitro produced porcine embryos were analyzed. PGRMC1 and PGRMC2 (progesterone receptor membrane component 1 and 2) showed distinct expression. Next, the embryos were treated with two concentrations of progesterone (10 nM and 100 nM) for two different durations (from day...
全文获取路径: Elsevier  (合作)
影响因子:2.082 (2012)

  • progesterone 孕酮
  • receptor 接受体
  • effect 效应
  • component 成分
  • vitro 体外
  • development 开发
  • produced 出品
  • membrane 
  • porcine 猪的